Extended periods of milk accumulation result in reduced milk secretion, increased apoptosis and eventually, involution of mammary glands. The subsequent change in epithelial cell shape from a cuboidal to a flattened morphology as the alveoli distend with milk may initiate changes in protein and gene expression (mechanotransduction) triggering the process of involution (Davis et al., 1999).
Proceedings of the New Zealand Society of Animal Production, Volume 67, Wanaka, 403-406, 2007
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