During lactation, prolactin activates STAT5 (Signal Transducer and Activator of Transcription), which binds to conserved DNA sequence motifs in promoters of milk protein genes to stimulate their expression (Liu et al., 1997). At drying-off, mammary involution is characterised by a rapid decrease in milk protein gene expression (Goodman & Schanbacher, 1991), including ?S1-casein (Singh et al., 2008). The ?S1-casein promoter features... Continued
Proceedings of the New Zealand Society of Animal Production, Volume 69, Christchurch, 57-59, 2009
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