Zinc sulphate (0.35 g Zn/litre) in the drinking water of lactating dairy cows prevented the effects of both a mild natural spore challenge and the subsequent severe challenge of dosed sporidesmin. The changes recorded (serum gamma glutamyl transferase, liver and urinary bladder injury score, daily milk production and clinical and live weight changes) in the unprotected control group indicate considerable toxic injury whereas the changes in the group receiving zinc in drinking water were minimal indicating excellent protection. Water consumption records for the 2 groups did not indicate that the zinc treated water was substantially discriminated against.
Proceedings of the New Zealand Society of Animal Production, Volume 43, , 209-212, 1983
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