@conference {40194,
	title = {Effect of duodenal infusion of protein or amino acids on nitrogen retention of lambs consuming fresh herbage},
	booktitle = {Proceedings of the New Zealand Society of Animal Production},
	volume = {50},
	year = {1990},
	month = {Jan},
	pages = {43-47},
	publisher = {New Zealand Society of Animal Production},
	organization = {New Zealand Society of Animal Production},
	abstract = {The first two years of a breeding trial have shown that sires with   slow clearance of glucose after a glucose tolerance test will produce   progeny with similar slow clearance and leaner carcasses (Line 1), than   progeny from sires with fast glucose clearance (Line 2).     Six extreme animals from each Line were selected to study the   biochemical mechanisms controlling the effects seen in the breeding   trial. An euglycaemic clamp experiment involved infusing insulin at   three levels, 0.63, 3.46 and 6.29 mU/kg liveweight 0.75/min, each for   four hours. At the same time glucose was infused with adjustments to   maintain plasma glucose at basal levels. The amount of glucose infused   is a measure of the sensitivity of the peripheral tissues to insulin.     Line 1 animals required significantly (P<0.05) more glucose to maintain   euglycaemia during all three levels of insulin infusion. Because there   were differences in basal plasma glucose (Line 1:71, Line 2:61 mg/100ml,   P<0.05), glucose utilisation was corrected for basal glucose. Line 1   animals still had greater glucose utilization. Another measure of   insulin sensitivity is the change in glucose utilization relative to the   change in plasma insulin as insulin infusion increases. Line 1 animals   had a significantly greater insulin sensitivity index than Line 2   animals (0.505 versus 0.193, P<0.01) for the change from level 1 to   level 2. When corrected for differences in basal glucose, Line 1   animals were still significantly more sensitive to the increase in   insulin (0.680 versus 0.346, P<0.01).     Selecting animals for breeding by glucose tolerance produces sheep with   differences in glucose utilization by peripheral tissues. These   biochemical differences are important in partitioning nutrients for   deposition of lean or fat tissue.    },
	issn = {1176-5283},
	author = {Fraser DL and Hamilton BK and Poppi DP}
}
