@conference {41898,
	title = {Systems biology and metabolomics : Experimental and computational challenges},
	booktitle = {Proceedings of the New Zealand Society of Animal Production},
	volume = {66},
	year = {2006},
	month = {Jan},
	pages = {213-218},
	publisher = {New Zealand Society of Animal Production},
	organization = {New Zealand Society of Animal Production},
	address = {Napier},
	abstract = {High-throughput technologies in the era of post-genomics provide new opportunities to investigate complex biological systems. Data can be collected for a system of interest at the level of gene expression, protein expression and metabolite concentration changes and then used for the assessment of interactions of molecules. However, the vast amount of information also poses challenges for data management, analysis, and interpretation. This paper aims to outline the technical complexity and the sources of variation in the technologies involved in molecular systems biology and computational strategies for data integration. },
	issn = {1176-5283},
	author = {Cao M and Koulman A and Pacheco D and Lane GA and Rasmussen S}
}
@conference {41901,
	title = {Urinary biomarkers of forage feeding from ESI-MS/MS fingerprinting: exploratory studies},
	booktitle = {Proceedings of the New Zealand Society of Animal Production},
	volume = {66},
	year = {2006},
	month = {Jan},
	pages = {230-235},
	publisher = {New Zealand Society of Animal Production},
	organization = {New Zealand Society of Animal Production},
	address = {Napier},
	abstract = {The combination of metabolic profiling by a combination of broad-spectrum analytical methods and multivariate statistics offers new opportunities for obtaining a global over-view of metabolism. It also facilitates the discovery of metabolites which can serve as useful markers of biological processes or states ("biomarkers"). Fast liquid chromatography and electrospray ionisation mass spectrometry with collision-induced dissociation in an ion-trap (fast LC-ESI-MS/MS) has been applied to determine metabolic profiles of bovine urine samples. The samples were collected twice daily from groups of five lactating dairy cows grazing in four different forage management systems comprising different spatial and temporal allocations of ryegrass (Lolium perenne) and white clover (Trifolium repens). The data have been analysed by different multivariate statistical methods, and a number of candidate biomarkers of forage feed and diurnal processes have been identified. },
	issn = {1176-5283},
	author = {Lane GA and Fraser K and Cao M and Koulman A and Cosgrove GP and Death A}
}
