@conference {40860,
	title = {Seasonal changes in FSH and LH concentrations in ewes with gonadal hypoplasia: Evidence that steroid-independent mechanisms control seasonality in sheep?},
	booktitle = {Proceedings of the New Zealand Society of Animal Production},
	volume = {56},
	year = {1996},
	month = {Jan},
	pages = {367-369},
	publisher = {New Zealand Society of Animal Production},
	organization = {New Zealand Society of Animal Production},
	abstract = {Current hypotheses for the control of seasonality are based on the  premise that seasonal changes in sensitivity to ovarian steroid hormones  drive changes in reproductive status. Most studies have used the  ovariectomised, oestrogen-treated ewe as an experimental model, but such  animals may be influenced by previous entrainment or exposure to gonadal  steroids. This study uses an infertile animal - the homozygous Inverdale ewe  - as a unique },
	issn = {1176-5283},
	author = {McLeod BJ and Kyle SE and Ramsay MR}
}
@conference {40745,
	title = {Hormone secretion patterns associated with increased ovulation rates or with ovarian dysfunction in Inverdale (FecX) ewes},
	booktitle = {Proceedings of the New Zealand Society of Animal Production},
	volume = {55},
	year = {1995},
	month = {Jan},
	pages = {304-306},
	publisher = {New Zealand Society of Animal Production},
	organization = {New Zealand Society of Animal Production},
	abstract = {Ewes that are heterozygous (I+) carriers of the Inverdale gene  (FecX) have increased ovulation rate, whereas ewes that are homozygous  (II) for the gene are infertile and have {\textquoteright}streak{\textquoteright} ovaries in which  normal follicle development does not occur. A proportion of ewes with  streak ovaries develop structures that have some characteristics of  ovarian tumours. We have monitored the growth of ovarian structures and  (c) assess the effectiveness of using hormone concentrations to identify  the genotype of individual ewe lambs.    No differences in hormone secretion related to differences in ovulation  rate were evident between I+ and non-carrier (++) Inverdale ewes (mean  ovulation rates 3.1+/-0.22 ng/ml) nor inhibin concentrations of  gonadotrophins were consistently elevated (FSH 16.9+/-1.8 ng/ml; LH  4.5+/-0.5 ng/ml; N+14) and were comparable to those observed in  ovariectomised ewes. In contrast, inhibin was always undetectable  (<3.0I.U./ml). These patterns of hormone secretion often change  markedly when ovarian structures develop, with inhibin concentrations  increasing acutely, which in turn causes FSH levels to fall.    To assess the potential of using these differences to identify II  genotype, Inverdale ewe lambs were blood-sampled at two, five or seven  months of age. Over 95\% of II Inverdale ewe lambs had genotype assigned  correctly (confirmed by laparoscopy) on the basis of plasma FSH  concentrations alone.   },
	issn = {1176-5283},
	author = {McLeod BJ and Kyle SE and Ramsay MR and Manley TR}
}
