@conference {41482,
	title = {Pasture biotechnology - not as you know it},
	booktitle = {Proceedings of the New Zealand Society of Animal Production},
	volume = {64},
	year = {2004},
	month = {Jan},
	pages = {101-104},
	publisher = {New Zealand Society of Animal Production},
	organization = {New Zealand Society of Animal Production},
	address = {Hamilton},
	abstract = {As part of an ongoing project to identify quantitative trait loci (QTL) for economically important traits in New  Zealand dairy cows, a vaccine trial was conducted to measure the antibody response of 10 week old Friesian-Jersey  crossbred calves to two antigenic compounds of a clostridial vaccine (Clostridium novyi B and  Clostridium tetani  toxoids). Blood samples were collected from 469 calves prior to vaccination at 10 weeks of age, prior to re-vaccination  at 13 weeks of age and at 16 and 22 weeks of age. ELISA assays using conjugated rabbit anti-bovine IgG were  conducted for both toxoids. Correlations and explanatory variables were calculated using correlation and general linear  model (GLM) procedures in SAS. Antibody response to both toxins were relatively low after the first vaccination (week  13), but were boosted to high levels after revaccination (week 16). GLM analysis revealed a moderate sire effect  contributing to the variability seen in the 13 week test against C. tetani (P=0.001) and the 16 week test against C. novyi  (P=0.01). This variation in individual antibody response will be used in future research to identify genetic factors  controlling the acquisition of immunity.   },
	issn = {1176-5283},
	author = {Elborough KM and Hanley Z}
}
